Identifying heritable cancer risk one family at a time.
MEET OUR TEAM
HOLLY STESSMAN, PHD
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Genetic risk factors in familial cancers
Understanding the genetics of familial cancer syndromes can be essential for preventative care and family planning.
_______ Many families with evidence of transmitted risk alleles screen negative for classical genes (e.g., BRCA1 and MLH1) or receive a result of "undetermined significance". _______ Using a combination of sequencing, pedigree analysis, deep chart review, and functional assays we are working to resolve the genetic risk associated with developing cancer in hundreds of families that registered with Dr. Henry Lynch over his 40+ year career at Creighton University. |